Photocontrolled Binding and Binding-Controlled Photochromism within Anthracene-Modified DNA

نویسندگان

  • Jack Manchester
  • Dario M. Bassani
  • Jean-Louis H. A. Duprey
  • Luciana Giordano
  • Joseph S. Vyle
  • Zheng-yun Zhao
  • James H. R. Tucker
چکیده

Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.

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عنوان ژورنال:

دوره 134  شماره 

صفحات  -

تاریخ انتشار 2012